Insulin resistance is a significant determinant of sarcopenia in advanced kidney disease
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چکیده
منابع مشابه
Sarcopenia in chronic kidney disease.
Sarcopenia is a chronic condition associated with physiological aging process and is defined by the reduction of the mass, muscle strength and function. In Chronic Kidney Disease (CKD), sarcopenia is prevalent and is associated with increased morbidity and mortality and the occurrence of cardiovascular complications. By analyzing sarcopenia in patients with renal insufficiency, complex mechanis...
متن کاملInsulin resistance and coronary artery disease in non-diabetic patients: Is there any correlation?
Background: Cardiovascular diseases are the most common causes of death in the world and type 2 diabetes is one of them because it is highly prevalent and doubles heart disease risk. Some studies suggest that insulin resistance is associated with coronary artery disease in non-diabetics. The aim of this study was to evaluate the association of insulin resistance (IR) and coronary artery disease...
متن کاملSarcopenia in Chronic Kidney Disease Authors
Correspondence to: Viviane Angelina de Souza. Federal University of Juiz de Fora. Rua Padre Café, no 472/801, São Mateus. Juiz de Fora, MG, Brasil. CEP: 36016-450. E-mail: [email protected] The loss of muscle mass in Chronic Kidney Disease (CKD) is considered an important complicating factor, contributing to a sedentary lifestyle and compromising cardiovascular health due to increased morb...
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متن کاملMolecular Mechanisms of Insulin Resistance in Chronic Kidney Disease
Insulin resistance refers to reduced sensitivity of organs to insulin-initiated biologic processes that result in metabolic defects. Insulin resistance is common in patients with end-stage renal disease but also occurs in patients with chronic kidney disease (CKD), even when the serum creatinine is minimally increased. Following insulin binding to its receptor, auto-phosphorylation of the insul...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Endocrinology and Metabolism
سال: 2018
ISSN: 0193-1849,1522-1555
DOI: 10.1152/ajpendo.00070.2018